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Inhaled volatile anesthetics remain the most widely used drugs for maintenance of general anesthesia because of their
ease of administration and predictable intra-operative and recovery characteristics. Management of hemodynamic stability and early recovery is the most important part of a
standardized balanced technique. Given the low blood-gas
partition coefficients of isoflurane (1.4) and desflurane (0.42),
a more rapid emergence from anesthesia is expected compared
with traditional inhalation anesthetics.
Desflurane has the most rapid onset and offset of the volatile anesthetic drugs used for general anesthesia due to its
low solubility in blood.
Isoflurane is an inhalational anesthetic whose low solubility (blood/gas partition coefficient equals 1.4) permits a
rapid induction of and recovery from anesthesia.
The current study aims at comparing the hemodynamic,
emergence and recovery characteristics of isoflurane with
those of desflurane in general anesthesia for patients going to