الفهرس 
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Abstract
One hundred and twenty nine chronic hepatitis C patients were included in this study to assess noninvasive predictive factors for occurance of oesophageal varices. Thirty healthy subjects were added as controls. The chronic hepatitis C patients were 88 (68.2%) males and 41(31.8%) females while the 30 healthy controls were 20 (66.7%) and 10 (33.3%) females. According to CHILD classification 84 (65.1%) of patients were CHILD A, 25 (19.4%) of patients were CHILD B, and 20 (16.5%) were CHILD C.
The laboratory characteristics of all patients showed that there were significant differences regarding albumin, cholesterol, adiponectin, HOMA-IR between CHC patients and healthy controls.
The sonographic findings showed that there were significant differences in portal vein diameter, splenic vein diameter, spleen bipolar diameter and platelets / spleen diameter ratio between patients and controls.
The endoscpic findings showed that there were 79 (61.2%) of patients with oesophageal varices and 50(38.8%) of patients without oesophageal varices. presence of portal hypertensive gastropathy was in 40 (31%) of patients.
Multivariate logistic regression analysis showed that three variables were independently linked to the presence of OV. There were platelets / spleen diameter ratio, adiponectin, and HOMA-IR.
HOMA value ≥ 3, adiponectin ≥ 18.5, and platelets count/spleen diameter ratio level ≤ 945 are Cutoff values for prediction of oesophageal varices.
HOMA ≥ 3.5 and adiponectin ≥19 are Cutoff values for prediction of (I-II grades) small OV. While HOMA ≥ 5 and adiponectin ≥ 21.5 are Cutoff values for prediction of (III-IV grades) large oesophageal varices.