الفهرس 
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Abstract
The objective of the present study was to evaluate the changes in the
concentrations of the major blood proteins and serum IL-6 level associated with experimental E. coli and S. aureus infection in rabbits. For that, 18
male Dutch rabbits (12 wk old) were divided into: 6 rabbits in the control
group (group 1) whereas in one assay group: 6 rabbits were
intraperitoneally injected with abacterial suspension of enteropathogenic
E. coli strain type 0157: H (group IT) and the other assay group: 6 rabbits
injected by the same way but with S. aureus bacterial suspension (group
Ill).
The collected samples were then centrifuged at 10.000 x g in ordinary
centrifuge for serum separation.
Serum IL-6, total protein, albumin and globulin fractions
concentrations as well as A/G ratio (protein electrophoresis) were measured
before (Oh) and after 24, 48, 72 and 96 hours from the bacterial injection.
Determination of serum IL-6 concentrations:
Tn the present study, the IMMULITE and TMMULITE 1000 Analyzers
was used for the quantitative measurement of interleukin 6 (IL-6) in rabbit
serum during a primary EPEe 0157: H and pathogenic Staph. aureus
infections.
Although all the infected rabbits show no clinical signs of disease,
both S. aureus and E. coli stimulate the production ofIL-6 comparing with
the control group and it began to increase dramatically till clearly observed
in the s” and ill day of the infection and there was a significant increase in
group lTI (exposed to S. aureus) than group IT (exposed to E. coli). I