Search In this Thesis
   Search In this Thesis  
العنوان
A Study On The Protective Role Of Ascorbic Acid As Antioxidant Against Ehe Toxicity Of Aluminium In Mammals =
الناشر
Ahmed Mahmoud Ahmed El-Morsy,
المؤلف
El-Morsy, Ahmed Mahmoud Ahmed.
هيئة الاعداد
مشرف / مرفت سيد حسن يوسف
مشرف / مختار ابراهيم يوسف
باحث / احمد محمود احمد المرسى
مشرف / مرفت سيد
الموضوع
Environmental Studies.
تاريخ النشر
2005 .
عدد الصفحات
141 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علوم البيئة
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة الاسكندريه - معهد الدراسات العليا والبحوث - Environmental Studies
الفهرس
Only 14 pages are availabe for public view

from 162

from 162

Abstract

The present study was carried out in the Hormone Laboratory at the Department of Environment Studies, Institute of Graduate Studies and Research, Alexandria University. The aim of this study was to determine the effect of aluminum chloride (AlCl3) on productive, reproductive performance and digestibility coefficients and nutritive value of male rabbits, protective role of AA against the toxicity of aluminum and the effect of AA alone on the above parameters. The results can be summarized as follow:
1- Aluminium chloride had adverse effect on body weight, feed intake, drinking water and protein intake. Also, feed conversion ratio, digestibility of dry matter (DM), organic matter (OM), crude fiber (CF), crude protein (CP), ether extract (EE), nitrogen free extract (NFE), nitrogen balance and nutritive values (TDN and DCP) were decreased. While, slaughter performance and organ weights were insignificant decrease .
2- Aluminium chloride had adverse effect on the activity of plasma and brain acetylcholinesterase (AChE) and glutathione S-transferase (GST) were significant decrease, and caused significant increase in aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (AlP) and acid phosphatase (AcP).
3- Aluminium chloride caused significant increase in the levels of thiobarbituric acid-reactive substances (TBARS) in plasma.
4- Aluminium chloride caused significant decrease in semen sperm concentration, total sperm output (TSO), ejaculate volume (EV), sperm motility (%), total motile sperm (TMS), total functional sperm fraction (TFSF), semen initial fructose (IF) and packed sperm volume (PSV). While, caused significant increase in dead sperm, semen initial hydrogen ion concentration (pH) and reaction time (RT).
5- Aluminium chloride caused significant decrease in the activities of GST, AST, ALT and AcP in seminal plasma.
6- Aluminium chloride caused significant increase in TBARS in seminal plasma.
7- Ascorbic acid alone caused increase in body weight, feed intake, drinking water and protein intake. Also, feed conversion ratio, digestibility of DM, OM, CP, EE, CF, NFE, NB and nutritive values (TDN and DCP) were increased. In addition, slaughter performance and organ weights (testes and epidydemis) significantly increased.
8- Ascorbic acid caused significant increase in the activity of glutathione S-transferase (GST). While, the activity of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (AlP) and acid phosphatase (AcP) were decreased. On the other hand, AA alone did not cause any change in the activity of acetylcholinesterase (AChE).
9- Ascorbic acid alone caused significant decrease in thiobarbituric acid-reactive substances (TBARS) concentrations in plasma.