الفهرس 
(C) Amylin Peptide HormoneOnly 14 pages are availabe for public view
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Abstract
The infants of diabetic mothers may have higher risks for serious problems during pregnancy, at birth and after pregnancy. Feed intolerance is a major problem occurring in infants born to diabetic mothers (Lee-Parritz, 2004). It is suggested that high serum amylin levels observed in IDM may be partially responsible for the feed intolerance seen in this population (Kairamkonda et al, 2005). Amylin peptide hormone is 37 amino acids hormone and belonging to calcitonin gene related peptide and co-secreted with insulin from pancreatic β cells in response to entral nutrient intake (Reda et al, 2002).
The present study aimed to measure the level of amylin peptide in a cohort of infants of diabetic mothers and to assess its relation to the feeding intolerance that develops in those babies.
This study was conducted on 30 infants of diabetic mothers (13 males and 17 females) and 15 full term control babies (9 males and 6 females), from Obstetric and Gynaecology Department and followed up at Pediatric Department, Faculty of Medicine, Ain-Shams University during the period from 1st April, 2006 and 1st February, 2007. Umbilical cord blood samples were analyzed for serum amylin and insulin.