الفهرس 
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Abstract
In all mammalian species studied, a system of closely linked genes oalled the major histocompatibility complex ”i.iHC” has been recognizea. In humane, this MHC system is called the human leucocyte antigen ”HLA” system, while in the mouse, it is called the H-2 system, History;
The HLA system nas developed out of a search for blood groups of leucocytes that could form the oasis for matching Qoners and recipients for transplantation.
Landsteiner in his Nobel lecture in 1931, had eraphai-
zed the parallelism between the problems of matching for
blood transfusion and for transplantation end advocated a search for blood groups for matching for transplantation using serological techniques,
In 1958, using sera from transfused patients, Ifeusset had demonstrated the existence of a specific leucocyte iso-antigen, which he christened ”;,LdC”, later to become HLA-A-,.
Further development depended on the independent discovery by two workers in 195S that leucocyte agglutinlns were produced by fetal maternal stimulation ^*
The development of the HLA system has been greatly stimulated by a series of international collaborative work-shops that were nameo international histocompatibility workshops. The first workshop was