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Abstract
Ischemic stroke is a wide spread disease affecting large number of population and causing a great mortality and morbidity with the accompanying social, psychological and economic problems.The great variability of outcome seen in stroke patients has lead to an interest in identifying predictors of the outcome.
Not only survival was the aim of researchers but also survival in an independent state is the aim of the physician, the patients and the caregivers.The current study was designed to assess the value of serum Neuron-Specific Enolase level and Pulmonary Functions as predictors of early clinical severity and extent ofneuronal damage in ischemic stroke patients.This study was conducted on 60 patients with acute ischemic stroke attending the Neurology Unit of Neuro-psychiatric department.
Faculty of medicine, Minoufiya University.
The included patients were subjected to;full history taking, general examination, complete neurological examination, laboratory workup [serum neuron-specific enolase (NSE),serum albumin, serum uric acid (SUA), blood glucose, erythrocytic sedimentation rate (ESR)].
They were also subjected to radiological imaging of the brain using computed tomography (CT).Patients’ condition was assessed with 3 clinical scales performed by ie same examiner on admission (within 24h of stroke onset), and repeated ubsequently at day 30 post stroke. The used scales were: national sstitutes of health stroke scale (NIHSS) score, BartheFs Index (BI) and icandinavian stroke scale score (SSS). Pulmonary function of the schemic stroke patients was evaluated by flow volume loop.They were 38 (63.3%) males and 22 (36.7%) females. Forty-five prcent (n=27) of the patients had left-sided cerebral infarction, while the|(her 55% (n=33) had right-sided cerebral infarction. The cerebral 118 Ischemic stroke is a wide spread disease affecting large number of population and causing a great mortality and morbidity with the accompanying social, psychological and economic problems.The great variability of outcome seen in stroke patients has lead to an interest in identifying predictors of the outcome. Not only survival was the aim of researchers but also survival in an independent state is the aim of the physician, the patients and the caregivers.The current study was designed to assess the value of serum Neuron-Specific Enolase level and Pulmonary Functions as predictors of early clinical severity and extent ofneuronal damage in ischemic stroke patients.This study was conducted on 60 patients with acute ischemic stroke attending the Neurology Unit of Neuro-psychiatric department.
Faculty of medicine, Minoufiya University. The included patients were subjected to;full history taking, general examination, complete neurological examination, laboratory workup [serum neuron-specific enolase (NSE),serum albumin, serum uric acid (SUA), blood glucose, erythrocytic sedimentation rate (ESR)].
They were also subjected to radiological imaging of the brain using computed tomography (CT).Patients’ condition was assessed with 3 clinical scales performed by ie same examiner on admission (within 24h of stroke onset), and repeated ubsequently at day 30 post stroke. The used scales were: national sstitutes of health stroke scale (NIHSS) score, BartheFs Index (BI) and icandinavian stroke scale score (SSS). Pulmonary function of the schemic stroke patients was evaluated by flow volume loop.They were 38 (63.3%) males and 22 (36.7%) females. Forty-five prcent (n=27) of the patients had left-sided cerebral infarction, while the|(her 55% (n=33) had right-sided cerebral infarction.
The cerebral 118 Ischemic stroke is a wide spread disease affecting large number of population and causing a great mortality and morbidity with the accompanying social, psychological and economic problems.The great variability of outcome seen in stroke patients has lead to an interest in identifying predictors of the outcome. Not only survival was the aim of researchers but also survival in an independent state is the aim of the physician, the patients and the caregivers.The current study was designed to assess the value of serum Neuron-Specific Enolase level and Pulmonary Functions as predictors of early clinical severity and extent ofneuronal damage in ischemic stroke patients.This study was conducted on 60 patients with acute ischemic stroke attending the Neurology Unit of Neuro-psychiatric department. Faculty of medicine, Minoufiya University. The included patients were subjected to; full history taking, general examination, complete neurological examination, laboratory workup [serum neuron-specific enolase (NSE),serum albumin, serum uric acid (SUA), blood glucose, erythrocytic sedimentation rate (ESR)]. They were also subjected to radiological imaging of the brain using computed tomography (CT).Patients’ condition was assessed with 3 clinical scales performed byie same examiner on admission (within 24h of stroke onset), and repeated ubsequently at day 30 post stroke. The used scales were: national sstitutes of health stroke scale (NIHSS) score, BartheFs Index (BI) and icandinavian stroke scale score (SSS). Pulmonary function of the schemic stroke patients was evaluated by flow volume loop.They were 38 (63.3%) males and 22 (36.7%) females. Forty-five prcent (n=27) of the patients had left-sided cerebral infarction, while the|(her 55% (n=33) had right-sided cerebral infarction. The cerebral