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العنوان
The effect of 2-chloroadenosine ( adenosine receptor agonist ) on the inflammatory response in rats /
المؤلف
Abu El-Safa, Enas Ali.
هيئة الاعداد
باحث / Enas Ali Abu El-Safa
مشرف / Mohamed Ibrahim Ahmed Ibrahim
مناقش / Adel Hussein Omar
مناقش / Maha Ahmed Fathy
الموضوع
Pharmacology.
تاريخ النشر
1999.
عدد الصفحات
105 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
1/1/1999
مكان الإجازة
جامعة المنوفية - كلية الطب - Pharmacology
الفهرس
Only 14 pages are availabe for public view

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from 102

Abstract

Inflammation is responsible for tissue injuiy in pathological conditions ranging from myocardi a! infarction to rheumatoid arthritis Recent studies suggest that adenosine is a potent regulator of the inflammatory response and, as such, may be useful as a phannacological agent in the therapy of inflammatory diseases The aim of this work was to investigate the effect of 2 -chlot oadenosine (adenosine receptor agonist) on the inflammatory responses in rats.Sixty six albino rats of both sexes weighing about 1 50-200 grams each and 30 mice of both sexes weighing 23-25 grams each, were used in this work. These animals were classified for induction of the different experimental models of inflammation They include acute and chronic experimental models of infiamniati on. The acute models of inflammation including carrageen an rat paw oedema and carrageenan induced inflammation in murine air pouch while the chronic model includes the adjuvant induced arthritis.