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Abstract The human major histocampatibility system (HLA system) is a cluster of inter-related genes which have been mapped to the short arm of the sixth chramosame and their products the hla antigens are expressed on the surface of almost all nucleated cells of the body. This system has a number of important function which include its role in the development and susceptibility to diseases especially those with known or suspected hereditary element, diseases with a possible immunological . |