الفهرس | Only 14 pages are availabe for public view |
Abstract Chronic HCV infection has been associated with a variety of extrahepatic disorders, in which either immunological or cytopathic mechanisrn are likely to play a role. Accordingly, it is postulated that HCV infection is not only a liver disease but rather a systemic infection that affects other, organs of the body. It has been observed that HCV infection is associated with development of DM. The aim of this work is to study whether a n-cell dysfunction with decreased insulin release or insulin resistance with decreased tissue sensitivity to insulin or both are present in patients with chronic HCV infection. Our study was conducted on three groups of subjects: Group 1: 20 type 2 diabetic patients with hepatitis due to HCV infection. Group 2: 20 type 2 diabetic patients. Group 3: healthy persons of same age and type as control group. Those patients were subjected to the following: 1- Full history talking. 2- Though clinical examination. 3- Fasting blood sugar and post prandial blood sugar. 4- Hepatic transaminases (SGOT, SGPT). 5- HCV Ab. (second generation). 6- Fasting insulin level. |