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العنوان
Insulin resistance and insulin secretion in type 2 diabetic patients with or without chronic hepatitis due to HCV infection /
المؤلف
Othman, Mohamed Fekri Ali.
هيئة الاعداد
مشرف / Mohamed Fekri Ali Othman
مشرف / Nabil El Kafrawi
مشرف / Ali Zaky Galal
مشرف / Ali Zaky Galal
الموضوع
Insulin resistance.
تاريخ النشر
2003.
عدد الصفحات
151 p. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
1/1/2003
مكان الإجازة
جامعة المنوفية - كلية الطب - MEDICINE General Medicine
الفهرس
Only 14 pages are availabe for public view

from 204

from 204

Abstract

Chronic HCV infection has been associated with a variety of extrahepatic disorders, in which either immunological or cytopathic mechanisrn are likely to play a role. Accordingly, it is postulated that HCV infection is not only a liver disease but rather a systemic infection that affects other, organs of the body.
It has been observed that HCV infection is associated with development of DM.
The aim of this work is to study whether a n-cell dysfunction with decreased insulin release or insulin resistance with decreased tissue sensitivity to insulin or both are present in patients with chronic HCV infection.
Our study was conducted on three groups of subjects:
Group 1: 20 type 2 diabetic patients with hepatitis due to HCV
infection.
Group 2: 20 type 2 diabetic patients.
Group 3: healthy persons of same age and type as control group.
Those patients were subjected to the following:
1- Full history talking.
2- Though clinical examination.
3- Fasting blood sugar and post prandial blood sugar.
4- Hepatic transaminases (SGOT, SGPT).
5- HCV Ab. (second generation).
6- Fasting insulin level.