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Abstract Coronary artery disease is a major cause of complications and death among patients with diabetes mellitus (Grundy et al., 2001). In particular, patients with diabetes are prone to a diffuse and rapidly progressive form of atherosclerosis, which increases their likelihood of requiring revascularization (Goraya et al., 2001, Luscher et al., 2002, Hurst et.,al 2003). Percutaneous coronary intervention and aortocoronary bypass surgery are recommended revascularization strategies for such patients. The role of PCI has been evolving over the last 2 decades. Coronary stent implantation has improved clinical outcome of diabetic patients compared with balloon angioplasty, primarily as the result of a reduction in acute complications and restensois rate (savage et al., 2002; Although coronary stenting has improved late outcomes (versus balloon angioplasty) The introduction of drug-eluting stents has reignited enthusiasm that PCI would again be at the forefront as a contender in revascularization strategies for diabetic patients (Morice et al., 2002; Moses et al., 2003, Schofer et al., 2003). Several studies have evaluated the effect of DES in diabetic patients in comparison with BMS bare metal stents which revealed better results in DES drug eluting stents regarding clinical and angiographic outcome. The results in the non diabetics still better that in non diabetics. |