الفهرس Only 14 pages are availabe for public view
 |  | from | 148 |  |  |
| | | from | 148 | | |
Abstract
Psoriasis vulgaris is a skin disease characterized by
hyperproliferation of epidermal keratinocytes, capillary elongation,
accompanied by inflammatory cell infiltrate. Keratinocytes
hyperproliferation could be explained by dysregulation of growth
factors controlling epidermal proliferation and by altered metabolism
of their receptors in affected skin.
Transforming growth factor beta 1 regulates the proliferation and
differentiation of cells, wound healing, and angiogenesis. It is a
potent inhibitor of cells as it arrests the cell cycle in the G1 to S
phases. It shows a multitude of effects on cellular differentiation and
growth.