![]() | Only 14 pages are availabe for public view |
Abstract In patients with acute myeloid leukemia, there are abnormal neutrophils which are morphologically normal but cytochemically abnormal and so called paraneutrophils, these neutrophils have preserved capacity of differentiation, considered as leukemic precursors, the granules of thses neutrophils contain the enzymes: Myeloperoxicase “P.O.X.”, neutrophila “N.A.P.” and chloracetate esterase, in patients with “A.M.L.” there is a high number of these paraneutrophil with marked decrease in the activities of enzymes: P.O.X., N.A.P., and C.A.E., while during the remission period the activities of these enzymes raised markedly. The present study was conducted on 31 newly diagnosed cases of acute myeloid leukemia, 15 males and 16 females, their ages ranged from 6 to 55 years 15 patients of the 31 were followed up. |