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Abstract
Granulomatous inflammation is a distinctive pattern of chronic inflammation due to infectious or non infectious agents. Its formation is due to the cell mediated immune response to such agents (Mitchell and Cotran, 2003; Dov, 2003).
Granulomatous inflammatory disorders involving the CNS have a wide variety of etiologies, clinical presentations, overlapping with each other and with other CNS disorders. And up till now, they have non conclusive investigations results making rapid accurate diagnosis sometimes difficult or impossible without tissue biopsy. Also many medical specialties are involved in the management of such cases, which leads to a lack in comprehensive integrated approach (Metwally, 2006).
Tuberculosis remains a major global problem and a public health issue of considerable magnitude, and was declared as a global emergency in 1993 by the World Health Organization (WHO). This was due to spread of HIV and multiple antituberculus drug resistance (Dolin et al., 1994). Common presentations of CNS tuberculosis include basal meningitis, focal cerebral lesions, myelopathy, Pott’s disease, rarely myelitis. In young age it may present with rapid onset encephalopathy