الفهرس 
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Abstract
Nosocomial infections (NI) are defined as those arising after 48 hours of hospitalization. They may result from exposure to pathogens from other patients, hospital personnel, the environment, or as endogenous infections. NI occurs in about 5-10 of hospital admissions and most commonly involves the urinary tract, surgical wounds, the respiratory tract, or the blood stream. (108 ) Escherichia coli, Staphylococcus aureus, Enterococci, Pseudomonas aeruginosa, and coagulase-negative Staphylococci are the most frequently isolated organisms .It has a significant impact on the cost and quality of health care. Patients hospitalized in ICUs are 5 to 10 times more likely to acquire nosocomial infections than other hospital patients.(109) A device-related infection is an infection in a patient with a device (i.e., central line, ventilator, or indwelling urinary catheter) that was in use within the 48-hour period before onset of infection. ( 7 ) The aim of the work was to study device related nosocomial infection in intensive care units of Alexandria University students hospital; to describe the magnitude and determinants & to identify predominant microorganisms ; to assess knowledge, attitude and practice regarding device related nosocomial infection among physicians and nurses working in those units .The study included 400 patients admitted to the three units & ICU staff (22physicians and 45 nursing specialists). From each patient; sputum, urine, blood cultures & chest x-ray were taken on admission and on appearance of any sign and / or symptom of infection, APACHE II scoring system was also performed as soon as possible after admission then once daily as follow up to determine the change in patient status. Data was collected from physicians and nurses working in ICUs through a questionnaire to assess their knowledge and attitudes related to device related nosocomial infection and its control . Also an observation sheet was used to assess their practice . THE RESULTS OF THE STUDY CAN BE SUMMARIZED AS FOLLOWS: 1- A significant association between invasive device, the number of invasive devices at the same time, the number of insertions for the same device, the duration of invasive device & nosocomial infection was determined.