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العنوان
Lipid profile, apolipoproteins A and B in children with epilepsy,
الناشر
Ain Shams University. Faculty of Medicine. Department of Pediatrics,
المؤلف
Ghonamy, Ahmed Hanafy Ali
تاريخ النشر
2007 .
عدد الصفحات
146 p.
الفهرس
Only 14 pages are availabe for public view

from 131

from 131

Abstract

Epilepsy is characterized by occasional (paroxysmal), excessive, and disorderly discharging of neurons that can be detected by clinical manifestations, Electroencephalographic (EEG) recording, or both (Thomas and Gregory, 2003).
Epilepsy is not an uncommon problem in children, it has a prevalence of 3.5/1000 among Egyptian school children (Elkhayat et al., 1994).
The plasma lipoproteins are molecular complexes of lipids and specific proteins called apolipoproteins. These dynamic particles are in a constant state of synthesis, degradation and removal from the plasma. The lipoprotein particles include the Chylomicrons (CM), Very Low Density Lipoproteins (VLDL), Low Density Lipoproteins (LDL), and High Density Lipoproteins (HDL). Lipoproteins function both to keep lipids soluble as they transport them in the plasma, and to provide an efficient mechanism for delivering their lipid contents to the tissue. In humans, the delivery system is less perfect than in other animals, and as a result, humans experience a gradual deposition of liquid-especially cholesterol-in tissues. This is a potentially life-threatening occurrence when the lipid deposition contributes to plaque formation, causing the narrowing of blood vessels-a condition known as atherosclerosis (Champe et al., 1994).