الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Many authors discovered treatment failure during management of many serious infections caused by Gram negative bacilli by intake of third generation cephalosporins, in spite of the standardized anti-moicrobial susceptibility work-up done before decision making (Ann et al., 2004).The aim of this study was to detect and characterize several phenotypes of inducible ~-lactamase production using Kirby-Bauer Disk Approximation(KBDD) methods. The interpretation of antibiotic susceptibility was based on a combination of inhibitoiy zone size and zone morphologies near a potent agent of J3-lactamase induction.In the present study, 50 different clinical samples were included,such as lower respiratory infections (sputum and bronchoalveolar lavage),urine, wound infections, blood, and cerebrospinal fluid, in which there was gram negative bacilli isolated with proven susceptibility to 3~ generation cephalosporins by standardized Kirby-Baur disk diffusion test and MIC determination by broth dilution. All isolates were further tested for inducible f3-lactamases by disc approximation technique.