الفهرس 
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Abstract
Infection with C.trachomatis is the most common sexually transmitted disease in many parts of the world, and its incidence has significantly increased in the past few years. The spectrum of the disease caused by C.trachomatis infection in women includes, asymptomatic illness, crevicitis, urethritis, salpingitis pelvic inflammatory disease, infertility, ectopic pregnancy, and abortion. Infants born to mothers with genital chalmydial infection have a high risk of contracting the infection during vaginal delivery in the form of conjunctivitis and pneumonia. Many studies have reported an association between chlamydial genital infection and increased risk of repeated abortion, intrauterine fetal death, premature rupture of membranes, and ectopic pregnancy. Detection of C.trachomatis is very important in diagnosis and treatment because a substantial proportion of infected women are asymptomatic and symptoms of infection are not specific. Diagnosis of C.trachomatis includes isolation by cell culture or detection of chlamydial antigen. Indirect methods of diagnosis includes the detection of antichlamydial antibodies in serum. The aim of this study is 1- To study the possible role of C.trachomatis infection with the outcome of pregnancy. 2- Evaluation of antigen detection by different methods in relation to antibodies for diagnosis of C.trachomatis infection. This study was carried out on 178 women attending the out patient clinic of EL-Shatby Maternity University Hospital complaining of repeated abortion, intrauterine fetal death, premature rupture of membranes, and ectopic pregnancy. Another 184 women with normal pregnancy were included as controls. All relevant informations were obtained from every woman and recorded in a questionnaire sheet. Three endocervical swabs were taken from every woman. One swab was rubbed on a glass slide for Giemsa stain examination, the second one was subjected to rapid antigen detection by IC , and the last one was transported in sucrose phosphate buffer for yolk sac inoculation. Serum samples were obtained for detection of IgG & IgA antichlamydial antibodies.