الفهرس | Only 14 pages are availabe for public view |
Abstract Nuclear cardiac imaging has become one of the most important non invasive tools in diagnosing, risk stratification and subsequent evaluation of coronary artery disease. Technetium-99m sestamibi is one of the most promising nuclear perfusion agents. Although thallium-201 (T1-201) is the most widely used clinical perfusion agent, technetium-99m sestamibi offers several advantages. It is available 24 hours, the energy of Tc-99m is140 KeV which is ideal for gamma camera imaging thus resulting in improved resolution, it has a much shorter half life (6 hours), and has minimal or no redistribution. Consequently, the use of Tc-99m agent has increased and expanded in the nuclear cardiology field. The aim of the present study was to evaluate the ability of Tc-99m sestamibi in predicting presence of chronic total occlusion in ischemic patients with no evidence of previous myocardial infarction. This study included 34 patients with no clinical evidence of previous myocardial infarction. Thirty four patients had chronic total occlusion of one or more of their native coronary arteries in their coronary angiograms. All 34 patients were subjected to coronary angiography. Thirty four patients had chronic total occlusion of one or more of their native coronary arteries. There were chronic total occlusion of 26 of the left anterior descending arteries (76.5%) chronic total occlusion of 8 (23.5%) of left circumflex arteries, and chronic total occlusion of 9 (26.5%) of right coronary arteries. There were 42 (41.2%) chronic totally occluded arteries by coronary angiography, 26 (62.8%) of these arteries were suspected of being totally occluded as shown by Tc-99m sestamibi SPECT. |