الفهرس 
Pathophysiology of ischacmic strokeOnly 14 pages are availabe for public view
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Abstract
Occlusive stroke is a widespread disease affecting large number of population and causing great mortality and morbidity with the accompanying social, psychological and economic problems and great health care costs. Neuologists were highly motivated to find an effective treatment which can decrease stroke mortality and minimize the resulting neurological deficit.
This study was designed to assess the value of either unfractionated heparin, low molecular weight heparin or aspirin in management of stroke and their impacts on the outcome. Also, aimed at assessment the value of addition of vitamin B6, vitamin B 12 and folic acid to the treatment on the outcome of stroke patients.
This study was carried out on 60 patients with acute ischaemic cerebrovascular stroke whom were divided into 3 groups each one composed of 20 patients, group I received unfractionated heparin, group II received low molecular weight _ heparin, group III received aspirin and each of the groups were divided into subgroup (a) who received vitamins and subgroup (b) who didn’t receive vitamins in addition to treatment.
The patients in this study were subjected to: Full history taking, medical examination, complete neurological examination, laboratory work up for risk factors, ECG, Echo-cardiography, carotid duplex, CT scan (at the time of entery and after one month) and assessment of the severity of stroke using outcome scales, NlHSS and SSS (at the time of entery, after 14 days and one month).
The results of this study showed that:
• No statistically significant difference between the three groups as regards demographic factors, main clinical manifestations, clinical risk factors, laboratory findings, ECG and Echo findings, duplex findings.
• No statistically significant difference between the three groups as regards CT findings (site, size, side of infarction) also follow up CT findings.