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Abstract The objective of our study was to determine any association between the anti annexin V Ab IgG isotope and unexplained recurrent spontaneous abortion. Methods: 50 women were included in the study. They were divided in to two groups: GROUP 1 patient group: included 25 cases that had a history of at least two or more successive unexplained recurrent abortion in their first trimester. GROUP 2 control group: included 25 cases that had at least two successful pregnancies and no history of pregnancy loss. Results: We found that 10 cases of the 25 patients were positive for IgG ANX V Ab (40%), in contrast for 7 controls of 25 women found positive for IgG ANX V Ab (28%), and we found that 15 cases of 25 patients were positive (60%), in contrast for 8 controls of 15 women were found positive for IgM ANX Ab (53.3%). Conclusion: Anti annexin A5 antibody of class IgG or IgM measured before the beginning of pregnancy are not predictive of the outcome of the next pregnancy. |