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Abstract The conventional approach in handling a non vital tooth with a wide open apex is a procedure called ”apexification”. It is defined as a method of inducing apical closure through the formation of mineralized tissue in the apical region of a non vital immature permanent tooth. Calcium hydroxides was the most commonly used material in apexification. In 1999, a new material, mineral trioxide aggregate (MIA) was introduced for clinical use which has the ability to create an apical plug. The present study was carried out to evaluate mineral trioxide aggregate (MTA) apexification versus calcium hydroxide (Pulpdent) either clinically or radiographically. Thirty traumatized maxillary non-vital incisors with open apices were selected from children aged from 8 to 10 years old attending to outpatient clinic of Pedodontic Department, Faculty of Dentistry, Tanta University.The selected children were examined clinically and radiographically and basic data were recorded for comparison at follow up periods. The selected teeth were divided into two groups (15 for each). The treated root canals were filled with either mineral trioxide aggregate (Pro root MTA) or calcium |