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Abstract
Wounds can be broadly categorized as having either acute or chronic aetiology.
Acute wounds include surgical wounds, bites, burns, minor cuts and severe traumatoc wounds as lacerations.
Chronic wounds are most frequently caused by endogenous mechanisms associated with a predisposing condition that ultimately compromises the integrity of dermal and epidermal tissue.
Chronic wounds include leg ulcers, foot ulcers and pressure sores.
Cutaneous wounds of acute and chronic origin provide a favorable environmental for microbial growth. Exposure of subcutaneous tissue following a loss of skin integrity provides a moist, warm and nutritious environment which help microbial colonization and proliferation. The abundance and diversity of micro-organisms in any wound will be influenced by factors such as wound type, depth, location, level of tissue perfusion and the host immune response. Certain bacteria and fungi normally cover the skin and populate the gut in a commensal relationship that acts to limit the so called invasive, pathogenic microorganisms. However, when the body’s epithelial barrier is damaged and the host is physiologically or immunologically compromised, some commensal organisms may become colonizers and invaders.
This study was performed on 112 patients suffering from wound infection.
45 were suffering from infected from infected wound and 22 were suffering from infected diabetic foot.
Bacteriological pathogens were isolated from 41 cases with infected burn wound, 40 cases with infected surgical wound and all cases with infected diabetic foot.