الفهرس 
The processes atherosclerosisOnly 14 pages are availabe for public view
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Abstract
Atherosclerosis is a response of the arterial wall to a variety of initiating agents, with multiple pathogenic mechanisms contributing to the formation of the atherosclerotic plaques. Atherosclerosis causes distinct clinical manifestations depending on the circulatory bed affected and the characteristics of individual lesions, which may be quite heterogeneous. Atherosclerosis of the coronary arteries commonly causes angina pectoris and myocardial infarction. Atherosclerosis of the arteries supplying nervous system frequently provokes transient cerebral ischemia and strokes. In peripheral circulation, atherosclerosis can cause intermittent claudication and gangrene. Involvement of the splanchnic circulation can cause mesenteric ischemia and bowel infarction.Atherosclerosis can affect kidney directly causing renal artery stenosis. Dyslipidemia is one of three major modifiable risk factors for coronary artery disease. Hypertension and smoking, are the other two factors. Many. studies have demonstrated that modified or oxidised lipoproteins play a key role in the process of atherogenesis, particularly in hyperlipidemic individuals. Recently, a great interest has revived in triglycerides (TG), hence authors have included the discovery of TG-rich lipoproteins in atherosclerotic plaques. High density lipoproteins exert several antiatherogenic effects. They participate in metabolic pathways that retrieve cholesterol from the arterial wall, and they inhibit the oxidation of atherogenic lipoproteins. There have been several reports demonstrating the important role of lipid peroxides in atherosclerotic disorders and aging process. The oxidative stress hypothesis postulates that endogenous free radicals of unknown origin, possibly derived from mural cells, oxidize low density lipoproteins and that oxidation products are allegedly responsible for initiation and progression of atherosclerosis.