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Abstract percutaneous transluminal coronary angioplasty (PTCA) has become a commonly employed technique of myocardial revascularization over the last decade. However, the fiequent occurrence ofrestenosis following 30% to 40% of initially successfbl procedures within the fmt 6 months remains the major limitation of the technique’’). Several trials demonstrated that diabetic mellitus is independently associated with a substantially greater incidence of restenosis over the 6 months period after balloon angioplasty(? The early divergence of ischemic event rates between diabetic and non-diabetic patients after PTCA corresponds to the period of highest risk for resteno~is(~). Intracoronary stent implantation has been shown to significantly reduce angiographic restenosis in human. The better long-term angiographic result is due to a better acute result and to the prevention of chronic remodeling despite an increase in neointirnal hyperplasia. It is unclear if these favorable results may be extended to diabetic patientd7). |