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Abstract - 90 - SUMMARY .AND CONCLUSION The Aim of the Work:- The aim of the work is to s~udy the effect of corticosteroidson glucose tolerance of asthmatic diabetic patients. Our work was done on tWilnty patients which were classified into two groups. Group I: Composed of ten diabetic patients, 5 of them were males and 5 were females, their ages ranged between 45 _ 60 years, their body weight ranged between 60 -91 kg, and duration of diabetes ranged between 1 - 13 years. Group II: Composed of ten asthmatic diabetic patients 5 of them were males and 5 were females their ages ranged between 42 - 63, their body weights ranged between 63 _ 90 kg, the duration of diabetes ranged between 3 _ 11·years, and the duration of asthma ranged between 1 - 12 years. The following were done for all patients: (1) Completehistor.Y taking. - 91 - (2) Family history of diabetes and asthma. (J) Past-history of other metabolic or endocrinal disorder, and the type and dose of treatment used. (4) FUll medical examination including all system6 - . .’- (5) Fasting and 2 hours postprandial blood sugar,serum cholesterol, creatininla,md blood urea estimation. (6) For asthmatic patient all the previous steps were done and the following were added. a- Pulmonary function tests. b- Blood examination. c- Sputum examination. d- Chest x-ray. e- Skin tests to detect the specific an~ig@n. For all patients glucose tolerance curve and double sample tests were done. All patients were treated with prednisolone in adose of l5mg!day for 4 weeks, then glucose tolerance and double sample tests were repeated. - 92 - The results: 1- 90’}&of the diabetic patients had no significant changes in their glucose tolerance and their blood glucose level when treated with prednisolone. 2- 80% of the asthmatic diabetic patients had insignificant changes in their glucose tolerance and their blood glucose level when treated with prednisolone. J- On comparing glucose tolerance of both groups, there was no significant difference and asthma has no significant effect on glucose tolerance and blood glucose level. |