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Abstract Nausea and vomiting of pregnancy begins between the fourth and seventh week after the last menstrual period and cease by 12 weeks tn 60”10of affected women. About 9O.ie of affected women have symptoms lbat persist beyond 16 weeks and may persist until 22 weeks (If gestation (Logioll d 1’Il., J003). Hyperem,esis gravidarum is a severe form of nausea and vomiting in pregrumc.y. often essocisted with weight loss, ketonemia, ketonuria, dehydration, electrolyte imbalaince, and possible bepatic and renal damage necessitating hospitalization (Eliald •• e1 aL. 2000). The actual iacidence of hyper emesis gravidarum has not yet been established, but has been reported to be between 0.3% and 2% of all pregmant women (Davi&, 1(04) • Different biological and psychological factors may play a role in triggering hyperemesis gravidarum, Elevated serum steroid bonn one and aC.G. eoncernranoas as well as gastric motiUty disturbances in early pregnancy are thought to play a. role in this eolldition (BroU85an1 rutd Richter., 1998). Some studies have recently suggested that there is an association between hyperemes.is gravidarwn and helicobacter pylori infection (Frigo d aL, 1998;KGUI’OOIfi ,et d. 2002; Slririlt et tII., 2tJIU). HeHcobacter Pylori is curved Of spiral shaped, Gram negative, noncapsulated non spore-forming bacillus. The organism measures (O.S-}) nm. in width and (2.5-5.0) om. in length. Helicobacter pylorus plays a major role in abdominal symptoms and g&SU’I.)-duodenal pathology (Suerlxlum lind BlllSer •• 20(1). |