الفهرس | Only 14 pages are availabe for public view |
Abstract Summary & Conclusion 88 SUMMARy 1- Mean PRA in breast fed infants aged 4-10 months was not significantly different from bottle fed . but infants fed on similac had significantly lower PRAthan those fed SMAformula. 2-Mean plasma aldosterone showed the same relatlonship . 3- Urinary sodium excretion in breast fed was not significantly different from the farmula fed. still infants on similac has sigificantly higher sodium excretion rates compared to those infants on SMA formula. and there was a correlation between urinary sodium and PRAand PAldo. 4- There was a significant correlation between PRA and Aldosterone in the three groups. 5- In relation to age. with PRA and PAldo. there was no sigificant correlation observed in the breast fed. but in bottle fed the hormonal levels showed a significant decrease with age. -- -- --- - - - - -- -- - ----------- Summary & Conclusion 89 CONCLUSION The maturation of the mineralo corticoids system ” plasma aldosterone - renin - angiotensin system ” is different in breast fed compared to formula fed infants . Infants fed on formula showed an earlier decline in the PRA and PALdlevel which occur in both the low sodium and the high sodium formula fed infants. The earlier decline was shown in the high sodium excretion group to be independent of PRA and PAId levels. It appears that the sensetivity of the PRA and PAId to sodium levels as a part of the heamostatic control mechanisms develops during infancy and is affected by the type of feeding during this period. The role of the breast feeding. in aiding to this maturational process is linked to absence of a correlation between age and PRA and PAId during infancy. The mechanism by which the latter finding is aided is not clearly defined. Whether prostag landins or other factors known to affect the Renin - Aldosterone. Angiotensin system exit in breast milk and playa role in the above findings remains to be investigated . |