الفهرس 
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Abstract
SUMMARY AND CONCLUSION
Chronic renal failure (C.R.F.) is one of the reported
causes of hyperamylasemia. Also. a high frequency of silent
or symptomatic pancreatic disease has been reported in
patients with C.R.F. Patients with C.R.F. frequently develop
G.I.T. symptoms.
The aim of this work is to study and interpret total
serum amylase activity in the context of the patient renal
status. mode of therapy and presence of other associated
medical diseases.
Thirty patients with C.R.F. (10 under conservative
treatment group II, 10 under P.D. group III. and other 10
under H.D. group IV. together with 10 normal persons as a
control group I) had been selected for this study.
None of them had any clinical or sonographic findings
suggestive of pancreatitis.
To all of them. full medical history, full medical
examination and the folloWing investigations had been done:
1- Blood urea. serum creatinine and abdominal ultrasonography.
2- Serum amylase determination (before and after dialysis and
once in groups I & II).
3- Serum triglycerides determination.
The results of this work showed
1) Significant elevation of the mean serum amylase activity in
all C.R.F. groups (80 % of cases) when compared to the
control group.
2) No significant difference between the mean serum amylase
values in different groups With C.R.F.
8)
3) Significant elevation of serum amylase activity after
dialysis in both H.D. and P.D. groups.
4) No correlation between serum amylase and either blood urea.
serum creatinine or associated liver disease.
5) Significant elevation in serum triglycerides in 36.7 % of
cases with C.R.F. when compared to the control group.
6) No correlation between serum amylase activity and serum
triglycerides in C.R.F. patients in different groups.
7) Significant lowering of serum amylase activity in C.R.F.
cases associated with diabetes millitus (D.M.) when
compared to the rest of cases.
Analysis of this results. its explanation. application
and clinical importance had been discussed.
from this stUdy. we come to the conclusion that:
1. Despite the frequency of hyperamylasemia in the setting of
C.R.F.• activities greater than 2 - 2.5 times of the upper
limit of normal have been considered unusual.
2. Serum total amylase is not affected by the mode of therapy.
3. It is not Possible to predict changes in serum amylase
activity on the basis of renal functional parameters.
4. Hypertriglyceridemia is a frequent disorder with C.R.F ..
but it is not correlated with serum amylase activity in
C.R.F. patients.
5. Cases With C.R.F. and D.M.
amylase and cases with C.R.F.
difference.
6. Diagnosis of pancreatitis in patients with C.R.F. must
depend on clinical. laboratory and radiological basis.
showed lower level of serum
and liver disease showed no