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العنوان
Prevention Of Postoperative Adhesions After Gynecological Microsurgery/
الناشر
Mohamed Abdel Hady Sayed,
المؤلف
Sayed,Mohamed Abdel Hady
هيئة الاعداد
باحث / Mohamed Abdel-Hady Sayed
مشرف / Gihan Allam
مشرف / Mohsen Khairy
مناقش / Gamal Serour
مناقش / Kamal Fahmy Abdel-Kader
الموضوع
Obestetric And Gynacology
تاريخ النشر
1989 .
عدد الصفحات
133p.:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/1989
مكان الإجازة
جامعة بنها - كلية طب بشري - النساء والتوليد
الفهرس
Only 14 pages are availabe for public view

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Abstract

Our study involved 60 sexually mature, healthy. isolated,
non-pregnant albino female rabbits. weighing two to three
kilograms each. The rabbits were housed individually for two
weeks prior to surgery. to be sure that they were not
pregnant.
Each rabbit was subjected to a standard injnry to
stimulate adhesion formation.
The rabbits were randomly divided into four groups, each
was made of 15 rabbits. The rabbits of each group received
one of the drugs to be tested for prevention of postoperative
adhesion formation/reformation. Each drug was administered
intramuscularly. 30 minutes prior to surgery, then every 8
hours for 3 successive days.
Group I: Rabbits in the control group received saline
injections. 1 ml per dose.
Group II: Rabbits received dexamethasone. 4mg/kg body weight
per dose.
Group III: Rabbits received promethazine. 7.5 mg/kg body
weight per dose.
Group IV: Rabbits received voltaren. 7.5 mg/kg body weight
per dose.
Four weeks later, a second laparotomy was done to assess
the adhesiion formation and lyse these formed adhesions.
Rabbits that developed intraperltoneal adhesions and had
adhesion lysis were again divided into 4 groups and were
given the previously mentioned drug regimens.
All the results were compared by the (Student t-test).
The study showed that each of dexamethasone and voltaren
was effective in reduction of postoperative adhesion
formation I reformation. However, there was no statistically
significant reduction of the adhesion formation I reformation
with the use of promethazine.
(1) Dexamethasone is effective in reduction of postoperative
adhesion formation I reformation.
(2) Voltaren is effective in reduction of postoperative
adhesion formation I reformation.
(3) The reduction of postoperative adhesion formation I
reformation was not significant with promethazine. compared
to control group.