الفهرس 
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Abstract
SUMMARY
(117)
SUMMARY
Our study involved 60 sexuallY mature, healthy, isolated non pregnant albino female rabbits, weighing two to three kilograms each. The rabbits were housed individually for two weeks prior to surgery, to be
sure that they were not pregnant.
Each rabbit was subjected to a standard injury to stimulate adhesion formation.
The rabbits were randomly divided into 4 groups, each was made of 15 rabbits. The rabbits of each group received intraperitoneally one of the drugs to be tested for prevention of postoperative adhesion formation:
Group I: Control group, received 30 ml of ringer’s lactate solution.
Group II: Received 30 ml of 6% dextran 70.
Group III: Received 30 ml of aprotinine (100,000 K.I.U. in 30 ml normal saline).
Group IV: Received 30 ml of 20% intralipid emulsion.
Four weeks’later, a second laparotomy was done to assess the adhesion formation and to lyse these formed adhesion.
Rabbits that developed intraperitoneal adhesions and had adhesion lysis were again randomly divided
018)
into 2 equal groups (30 animals in each). The rabbits of each group received intraperitoneally one of the drugs to be tested for prevention of adhesion reformation.
Group A: Received 30 ml of 6% dextran 70, Group B: Received 30 ml of aprotinine.
All the results were compared by the (gtudentig t-test).
The study showed that 20% intralipid emulsion significantly reduced postoperative adhesion formation. Eighty percent of intralipid-treated animals developed mild adhesions and 20% developed moderate adhesions. However, neither 6% dextran 70 nor aprotinine was effective in reduction of adhesion formation compared to control. In dextran-treated animals, 20% developed moderate adhesions and 80% developed severe adhesions. In aprotin ine-treated animals 6.7% developed moderate adhesions and 93.3% developed severe adhesions. In addition, 6% dextran 70 and aprotinine were not effec-tive in prevention of, adhesion reformation after adhesolysis, severe adhesions reformed in all dextran and aprotinine-treated animals.