الفهرس 
Material and methodsOnly 14 pages are availabe for public view
 |  | from | 128 |  |  |
| | | from | 128 | | |
Abstract
- 83 -
SUMMARY AND CONCLUSION
This study included forty cases, class if ied
according to semen analysis into subfertile, infertile
fertile groups. Estimation of serum and seminal plasma
prolactin was performed to clarify any possible role
of prolactin in male infertility.
prolactin concentrations in serum and seminal
plasma were measured by radioimmunoassay.
The following results were obtained:
A highly significant increase in serum pro~actin
in both asthenospermic and oligoasthenospermic groups,
an increase in serum prolactin in oligospermic group.
While no increase ~n serum prolactin in azoospermic
group compared to normal.
seminal
subfertile
plasma prolactin levels were increased
and infertile groups compared to normal
in
controls.
No signif icant correlation was shown between
serum and seminal plasma prolactin concentrations in any
of the subfertile or infelrtile groups.
- 84 -
A significant positive correlation between serum
prolactin and sperm count in oligospermic group. While
no significat correlations was shown between seminal
plasma prolactin and sperm count in any of the groups.
Regarding sperm motility, a signif icant negative
correlation was obtained between serum prolactin and
sperm motility in the asthenospermic group, also a
very highly signif icant posi ti ve correlation was
found in the oligoasthenespermic group. While no signif
icant correlations were obtained between seminal
plasma prolactin and sperm motility in any of the
groups.
These results are described in view of recent
clinical and experimental reports implicating hyperprolactinaemia
as a cause of male infertility.
It is assumed that the data obtained from this
study may be useful for further studies on the pathogenesis
of male sterility. As we came to a conclusion
that subfertile and infertile groupS had high seminal
plasma prolactin levels. Also hyperprolactinaemia
may affect sperm motility.
- 85 -
A recommendation arises from this study is the
determination of serum and seminal prolactin in patients
with fertility disturbances may be helpful to detect
a hyperprolactinaemia which may be responsible for
disturbances in hypothalamo-pi tui tary testicular axis,
further investigations for determination of luetinizing
hormone. follicle stimulating hormone and testosterone
is recommended. Also hormone profile determination
and correlation with histopathological studies in cases
of sperms obstruction or arrest.