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Abstract (88) SUMMARY AND CONCLUSION This work aimed to find a relation between the level of to ICAM-I and upper respiratory tract infections which procee complications as a prelimin step for the use of solubd le mmon colds w ICAM-1 as a protective treatmenary t for co causative viruses are rapidly changing. hose This study was carried out on 30 patients complaining of upper respiratory tract infections and/or its complications eal .g• otitis s investigations media. The patient were subjected to bacteriologi-c which they were classified as ira-tory tract infection due to bacterial agent (group I) upper andresp upper respiratory tract infection due to a non bacterial agenti, e. vi-ral, fungal (group II). The study showed that there was ence in almost all the no significant differ- parame ymphocytes count (absoluted level of IC ters done, i.e., white cell count, haemoglobin concentration, l relative), granulocytic count (absolute and relative ) and also AM-I in serum between the two between the groups and the reference group. grou ps and in- This study proved that there is no bacterial and non-bacterial u difference between pper respiratory tract infections as regards the concentration of the circulating solu AM-1, which has probably been bound to their receptors.ble This carry the hope of the assumption f night for the preparation of a synthetic soluble ICAM-I analog which might be used to from block the receptors of ICAM-1 and prevent the symptoms P to complication. This more work on a wider scale to verify or dispute need it. |