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Abstract Summary -------------- The human larynx is a marvelously dynamic structure serving as a protective gate to the lower respiratory tract. It has been adapted to produce speech in man which has contributed greatly to man’s ascendancy and to his commanding position in the animal kingdom. On the other hand laryngeal dysf’unction can lead to the isolation of”the individual and to a sense of’loneliness because of the inability to communicate normally and he is generally drown into seclusion because of his handicap. Hence, it is imperative to make a review on the studies, researches and achievements dealing with the laryngeal neuromuscular dysfunction. This eSSay is divided into five chapters. (1) AnatoillY01’ the larynx.: A briel’ review of the anatomy of the laryn.<: will help in understanding the physiologic mechanf. sms and. appearance oi: the laryILc in health and in disease. The laryILc consists of cartilagenous - 208- skeleton, the cartilages are held together by fibroelastic ligaments and membranes, moved by muscles and lined by mucosa. The larynx is supplied by the paired superior and recurrent laryngeal nerves derived on each side trom the vagus nerves. It is necessary to make a review on the physiologic functions of’the laryru, since the impairment of the physiologic fmlctions is the basis of the clinical aspect. It deals with the two most important functions Which are protection of the lower respiratory tract and-phonation. It covers both the neuromuscular and .erodynamic theories of the origin of the vibrations of the vocal cord. Circulatory function and its function as a receptive field for cough reflex are »errt i oneo briefly. Chapter tw.o alse presents the resptrF.ltory function with acid-base regulation • - 209 (3) ~~~~!~5l_~f_~~~_~~~~~~£~!~_~l~f~£~!~~: ~euromuscular dysfunction of the larynx has a myraid of causes located from the brain to the aortic arch level. Chapter three is divided into four diagnostic categories. 1) Neuralogical category which is subgrouped as peripheral and central neural disorders. 2) Myoneural junction category,due to rapid splitting of the acetyl choline as in myasthenia gravis or due to diminished reali~ing 01 the acetyl choline as in the lli,yasthenialike syndrome. 3) Myogenic category, includes illyotonia,myopathies, and dermatomyositis and polym,yositis. 4) Psychogenic group, conversion 01” the psychic conf’lict into spastic dysphonia, ventricular dysphonia, hysterical aphonia, and others are presented. In chapter four the diagnostic evaluation protocol is presented. It begins with the history and physical examination to include the laboratory - 210 - and radiologic studies. The diagnostic protocol includes also the panendoscopy and special tests. History wid physical examination are the mainstay in the diagnosis and if they do not clarify the etiology,laooratory and radiologic studies are necessary. Direct laryngoscopy is mandatory to determine the passive mobility of the arytenoid. The value of the special tests as a f’actor in achieving correct diagnosis are emphasized. The special tests which have been reviewed include electromyography. cornputarized a.c iaI tomographic scanning, voice tape recording, cinephotography, stroposcopy, andr)ulmOnary flow loop. (5) M.anagement; Chapter 5 covers the different procedures for the treatment of laryngeal dysfunctions. The treatment of the etiologic process is usually unrelated to the physiologic dysfunction. Before furgical interference other than tracheotomy, 6-12 mouths should be elapsed to 211 allow l’or spontaneous recovery or maximum compensation, i~ recovery has not occured one or other of several procedures, which have been presented,have been restored to restore the physiologic function. Bilateral abductor paralysis is much more important as the patients are at risk of total respiratory obstruction. Among the several procedures presented, nervemuscle pedicle reinnervation has special attention. Ji.veryPossible lines of treatmen.t 01’ unilateral abductor and adductor paralysis, bilateral adductor paralysis, and abductor and adductor types of Spastic dysphonia have also been presented. |