الفهرس 
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Abstract
F.M.F. is a disease of unknown origin, characterized
by recurrent febrile paroxysms of painful;serosal
inflammation that generally last several days and resolves
without sequalae.
Amyloid nephropathy is the most threatening
complications of F.M.F. patients which usually manifested
clinically by proteinuria.
Microalbuminuria indicates abnormal passage of
albumin through the glomerular filter and its prognostic
value has established in different diseases.
Our study has been done on 25 F.M.F. patients
and 20 normal subjects as control group aiming to evaluate
the presence or absence of microalbuminuria in F.M.F.
patients which may detect early renal affection in these
patients.
To all of them the following have been done to
exclude other conditions that may cause similar clinical
picture or may cause microalbuminuria:
(1) Full history taking.
(2) Full clinical examination.
(3) Laboratory investigations including:
(i) Urine analysis.
(ii) Complete blood picture & E.S.R.
(iii) Fasting and post prandial blood sugar.
(iv) Hepatic and renal function tests.
(4) Electrocardiography (E.C.G) 82
(5) Plain X ray chest.
(6) Abdomenal ultrasonography.
For selected cases of F.M.F. and control groups the
following have been done:
- Albumin in 24 hours collection of urine.
- Microalbuminuria in 24 hours collection of urine.
In this study we found the following:
- No rnicroalburninuria in all control group.
- Microalbuminuria is pressent in 14 cases out of 25 (56%)
and absent in 11 cases out of 25 (44%).
- Microalbuminuria has no significant relation to the age,
sex, body weight, body mass index, sample timing and
duration of the disease.
- There is significant relation between microalbuminuria
and colchicine treatment.
Thus from this study we can conclude that:
(1) The presence of microalbuminuria in patients with
F.M.F. may help in early detection of renal affection in these
patients.
(2) Microalbuminuria has no relation to the sex, age,
bodyweight, body mass index, sample timing and duration of
the disease.
(3) Colchicine therapy significantly reduce the
incidence of microalbuminuria and so may stop the
progression of renal affection in patients with F.M.F.
Recommendations
(1) Regular follow up of patient of F.M.F. every year by
testing the presence of absence of microalbuminuria is very
important.
2) Early treatment by colchicine therapy is of great
value in these patients.