الفهرس 
Nephrotic syndromeOnly 14 pages are availabe for public view
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Abstract
Hepatitis C virus (HCV) is an RNA virus causing both acute and’
chronic liver disease and is a major cause of both transfusion associated
and sporadic non- A non- B hepatitis .
Hepatitis C virus may be associated with immunologicallymediated
renal diseases.
The objective of this study was to detect the prevalence ofHCV
among Egyptian patients who were diagnosed previously as idiopathic
nephrotic syndrome and to study if it could have a possible etiologic role
in such patients .
Our study comprised 50 patients who were randomly selected
diagnosed as idiopathic nephrotic syndromefor whom kidney biopsy had
been carried out in Mansoura Urology and Nephrology Center in the
course of investigations, attending its outpatient clinics for follow up.
The study revealed high prevalence ofHCV infection among patients
with idiopathic nephrotic syndrome, specially patients of MPGN with
increasing age, presence ofhepatomegally, mildly elevated transaminases
and history of anti-bilharizial drugs. MPGN was the commonest
pathological type associated with HCV and hypocomplementemia.
We can recommend the routine screening of patients with
glomerulopathy for HCY, seroepidemiological studies involving larger
population of patients in various regions to specify the relationship
between HCY and glomerulopathy in the presence and. absence of
schistosomiasis and to define the characters which help to determine the
etiological factor which may be responsible,for these pathological changes,
follow up the patients for cryoglobulinemiaand to determine the strategy
for treatment of such cases and define the effects of their treatment on
HeV viremia, antibody response, renal and liver diseases.