الفهرس 
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Abstract
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(102)
SUMMARY AND CONCLUSIONS
This study was done on 31 mUltiparous, fertile
women attending the maternal and child health center
of Benha for contraception. Women were found to be
fit for applying IUCOs and agreed to have this method
of contraception. Women were divided into two groups.
The first group included 16 women who were fitted
with a lippes loops, while the second group included
15 women who were fitted with copper T-200 IUCOs.
Serum levels of prolactin were detected by
Radioimmunoassay before application of IUCOs, then
at one week and three months after application of
IUCOs.
In this study we found that:
1- There was no a statistically stgnificant changes
in mean serum prolactin level. one week after
insertion of IUCOs (P > 0.05l.
2- There was no statistically significan1:difference
between both groups (P > 0.05l.
3- Thore was statistically highly significant
increase of mean serum prolactin level three
months after insertion of both lippes and copper
T-200 IUCOs (P < O.Oll
(103)
4- There was a statistically highly significant
increase in the number of women with hyperprolactinemia
three months after lUCOs insertion
(p < 0.01).
CONCLUSIONS
Our study showed that there was a significant
increase of mean serum prolactin level three months
after application of both lippes and copper T-200
lUCOs. The cause of this increase can not be fUlly
explained, but probably a pituitary or uterine origin
of this prolactin increase may be the cause. The
increase of serum prolactin level, which was more
than 20 ng/ml in 17 women may be a possible mechanism
by which lUCOs exert their contraceptive effect.
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