![]() | Only 14 pages are availabe for public view |
Abstract In our study we detcrnJined serum llrohctin l~vels Q’Jl”ing noma 1pregnll.ncy i n ~ypt hn primigrav-idaa to knovr the Do~al levels which rrsy Earve $S B b~se for c~h~r 8tUdies in complicated pre6nencies, UsL~~ radioirr~unoassay method, we measured ef!r~ prolactin level in 110 llo’L’lllal primlgravidse dintributed over the period 8 to 4D weeks ge !lta~ 1c n • Serum prDInc t in Love 1 waa fo una. to r-i, se t:’lI’ou.- .’jhott:; prcgn;.ncy and to :::-eRch a ma::dmn.l leve 1 at t erm, At R weeks I the wean 3erUffi prolactin level wa~ 16.’3 ± 4.75 ngjrrl. It lnC~~ased si3niflcantly (p(O.Ol ) to 36 i 11.12 ng/~l at IG weeks. It alAo lnc~eased siEni£ica~tly (p ~ 0.01) to 90.5 t 29.27 DC / ~l at 28 ~.’<:eks• It real’:hed a max.ima.LLsveL o.t 308,::;3 t 103~8 I:l.g Iml (p ’-;0.001) at 4D ~IBe}l;s gestation. ’l’l1us serum p~olaetin. level in Egypthm’ primigravidae with normal pregnancy Lnc rea aed up to 19 folds r~om 8 weeks to 40 ~eeks gestaGlon • The range of” serllY:’. prn Lacti in level at 38 - 40 meeks WI’!!!wide beinG between 82’ aDd 489 ng/ml. The mean value during the first trimester ( 8 - 14 weeks of gestation) W~s 25.68 ± 9.61 ng/ml ( n ’” 22 ). It increasEd significantly ( F<O.OOl ) to a mean value of 57.88 ± 27.69 ng!ml(n ~ ~9) in the 2 nd trimester ( 16 - 28 weeks of g~~tation ) • During the 3 I’d ~rime~et~r { 30 - 40 weeks of gestation ) I the mean aer~~ prolactin vnlue was 218./«; ± 115.3? nelml which WaS significantly bigher than the 2 nd trimester ( p. < 0.001). Serum prolactin loval 8nd ~ts progrcs~iYe incrensa throughout nom.al pregnancy in F.€iypti’>n yl’imigt”avldae in QUI’ study are in. agreement with the results af studies in other coonteries+ |