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Abstract
Heart failure is defined as a state in which the heart cannot deliver an adequate cardiac output to meet the metabolic needs of the body. Because of the high total direct costs of care for heart failure, rapid and accurate differentiation of congestive heart failure from other causes of dyspnea must be accomplished-type natriuretic peptide is a cardiac neurohormone specifically secreted from the ventricles in response to volume expansion and pressure overload.B-type natriuretic peptide may be useful in distinguishing between cardiac and non cardiac causes of acute dyspnea. Recently, assay for B-type natriuretic peptide demonstrated that measurement of B-type natriuretic peptide added to the ability of the physician to diagnose congestive heart failure in the urgent care setting. This study was carried out on 50 patients presented with respiratory distress. Respiratory distress was classified as cardiac or non cardiac,30 patients had heart failure due to congenital or rheumatic heart disease (20 patients with congenital heart disease and 10 patients with rheumatic heart disease),17 patients were males and 13 patients were females, their age ranged from 1/12 years to 15 years with the median age 1.1 years. 20 patients had non cardiac cause of respiratory distress, their age ranged from 5/12-13 years with the median age 2.1 years. Ten apparently healthy infants and children of the same age, sex and socioeconomic status were taken as a control. The patients were attending the pediatric cardiology clinic, the pediatric intensive care unit and the inpatients pediatric department, Minoufiya university hospitals.