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العنوان
A study on the factors affecting susceptibility of different clinical isolates to certain chemotherapeutic agents and their combinations
الناشر
Cairo . Pharmacy . Microbiology & Immunology
المؤلف
Sharaf,Eman Abdel Fattah Ibrahim I.M.
تاريخ النشر
2005
عدد الصفحات
161 p
الفهرس
يوجد فقط 14 صفحة متاحة للعرض العام

from 338

from 338

المستخلص

A total of 157 clinical isolates were collected from hospitalized patients, of different sex and ages, in teaching hospitals in Egypt. Specimens were taken from different sites and included blood, urine, pus, sputum, bronchial fluid aspirates and others. Tentative identification of the isolates was carried out using routine laboratory methods including microscopical examination, classical biochemical tests and newly introduced methods such as VITEK 2 system, and by CHROMagar orientation medium. The total number of gram-negative isolates was 90 isolates (34 Pseudomonas aeruginosa, 27 E. coli, 25 Klebsiella species and 4 Proteus mirabilis) while the number of gram-positive isolates was 67 of which 39 were Staphylococcus aureus and 28 were Streptococcus species.
In case of respiratory tract infections, gram-negative bacterial isolates were more common than gram-positive isolates and Pseudomonas aeruginosa was the most common one followed by Streptococcus species. In bronchial fluid aspirates, both gram-positive and gram-negative isolates were almost equal. On the contrary, gram-negative isolates from wound infections were less common than gram-positive isolates and Klebsiella was the most common one than Pseudomonas aeruginosa. The most common gram-positive was Staphylococci followed by Streptococci species. .
In urinary tract infections, E. coli was the most predominant causative agent; it represents more than one half of the total cases. Gram-positive cocci were the least isolated bacteria; only 2 strains of both Staphylococci and Streptococci were isolates.
The main isolate from blood specimens was Staphylococcus aureus, representing about 54% of the total blood isolates. The other blood isolates, Pseudomonas and Klebsiella, were less common and only one isolate was E. coli.
The least number of isolates were from ascetic fluid, cerebrospinal fluid and bone marrow. Only one isolate from each site was recovered; one Streptococcus isolate from ascetic fluid and the other two isolates were Staphylococcus aureus.