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Abstract Portal hypertensive gastropathy (PHG) is a collective term that defines an array of diffuse macroscopic lesions observed in the gastric mucosa of patients with portal hypertension. It is generally diagnosed on the basis of endoscopic features. PHG is associated with mucosal and submucosal angiogenesis, vascular ectasia and dilation. Histologic comlirmation is needed when the lesions are not characteristic or when other conditions such as gastric antral vascular ectasia (GAVE), Helicobacter pylon infection, or drug-induced mucosal lesions need to be excluded and to follow up the effect of certain therapeutic applications on tissue level. Argon plasma coagulator (APC) is a new thermal modality that is intended for thermal coagulation of tissue. It has the major advantage that the depth of coagulation is automatically limited by a thin, electrically insulating layer which develops due to desiccation of the superficial tissue layer. Hemostasis is a main target for the use of APC and its role in ceasing PHG related acute and chronic bleeding is being studied in the past few years. This study was performed on 30 cirrhotic anaemic patients diagnosed endoscopically as having severe PHG. They were 13 males and 17 post menuposal females. Their ages ranged from 30 to 56 years with a mean of 50.7±2.9 years. All other possible causes of anaemia were |