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Abstract
Fatty liver defined as accumulation of fat, largely triglyeerides, exceeding 5% of the liver weight, or visualization of more than 5% of hepatocytcs containing fatty droplets on light microscopy. The disease is classified to non alcoholic fatty liver disease (NAFLD ) and alcoholic fatty liver disease ( AFLD ) .It is due to failure of normal hepatic fat metabolism either due to defect within the hepatocyte or to delivery of excess fat, fatty acid or carbohydrates beyond the secretory capacity of lipid of the liver cell. Non alcoholic fatly liver diseases (NAFLD) represents a spectrum of several clinicopathologcal entities from simple steatosis to cirrhosis including steatosis alone, steatonecrosis, steatohepatitis and histological alcoholic - like hepatitis. In the general population, the estimated prevelance ranges from 3%-24%, with most estimates in the 6% to 14% rangesAlcohol-induced liver disease can be divided into the following 3 groups: alcoholic fatty liver (simple steatosis), alcoholic hepatitis, and alcohol-related cirrhosis. Alcoholic fatty liver is an early and reversible consequence of excessive alcohol consumption Etiology of NAFLD --1 -- Standard (Classic) fctiobgicaC Factors -A) Nutritional abnormalities-1- Obesity - 2- Total parenteral nutrition -3- Choline deficiency -4- Rapid weight loss