الفهرس 
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Abstract
Morphometry is the quantification of changes in tissues, cells and organelles. The potential advantages of morphometry in histopathology and cytopathology have been recognized for many years. It is clearly preferable to the unaided visual assessment in that it is more objective and thus more accurate and reproducible.
The current work aimed at studying the diagnostic value of nuclear morphometrics in benign, pre-invasive and invasive ductal breast lesions and evaluating its prognostic importance together with other dmicopathologic factors including the proliferative activity.
In the present study we considered a total of 61 histologic sections of invasive duct carcinoma (IDC) of no special type, 12 cases of carcinoma in situ (DCI) and 14 cases of benign breast tissue taken from fibrocystic disease. Histologic grade of the IDC cases was done according to the Nottingham modification.
To cany out the morphometric measurements, the new assembled digitizing and image-analyzing device (DIAD) was used. The microscopic image was recorded by the video camera, digitized by the computer and displayed on the monitor screen. An average of 5-10 microscopic fields of magnification x 1000 was captured from each case and saved as JPG files. The following measurements were performed The mean nuclear area (MNA), mean nuclear perimeter (MNP), mean maximal nuclear diameter (MMND), mean minimal nuclear diameter.