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Abstract Microcytic anemia is a common category of anemia. Common causes _crocytic hypochromic anemias in children include: iron deficiency ia, thalassemia syndromes (f3-thalassemia,ct- thalassemia and thalassemic s), anemia of chronic diseases, sideroblastic anemia and to extent anemia of chronic lead poisoning if associated with iron a- thalassemia is perhaps the most common single gene disorder in the It occurs in individuals particularly those of African Asian, Central i, Mediterranean, and Middle Eastern descent. Emigration from in which carrier frequency is high increases the presence of r,_semia syndromes in other parts of the world. Diagnosis of a- thalassemia syndromes is still a laboratory problem. Co-inheritance of a- thalassemia determinants in 3- thalassemia disease as one of the ameliorating factor in thalassemia intermedia Dozygotes. s study was conducted upon two main study groups. The screened group included 511 children of microcytic hypochromic 318 (62.2 %) of them were male and 193 (37.8%) were females. r ages ranged between 6 months and 17 years with an age mean of 4.17 ,8) years and with mean Hb concentration of 7.99 (± 1.83) g!dl. The of the study of this group was to estimate the relative frequencies of t types of microcytic hypochromic anemia and to detect and diagnose of a- thalassemia. The selected group included 40 children of already diagnosed assemia intermedia, 15 were males and 25 were females. Their ages |