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العنوان
Synthesis of new 4 and 7 substituents of pyrrolo [2,3-d] pyramidines with expected biological activity /
المؤلف
Shalabey, Yahya Zakareya Mahamoud Ibrahim.
الموضوع
Chemistry. Organic chemistry.
تاريخ النشر
2006.
عدد الصفحات
70 p. :
الفهرس
Only 14 pages are availabe for public view

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Abstract

Derivatives of 2-aimino 1-aryi-5-pheny1-H-pyrrole-3-carbonitriles 4 were synthesized by the reaction of phenacylmalononitrile 3 with aniline derivatives in presence of conc HCI under reflux (scheme reaction of derivatives of 2-amino-1-ary1-5-pheny1-1H-pyrrole-3-carbonitriles 4 with 85% formic acid gave derivatives of 7-ary1-6-pheny1-3,7 dihydro-pyrrolo 2,3-d pyrimidin4-ones through the amide intermediate .