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العنوان
Synthesis and Spectroscopic Studies on N-Glycosidesof Quinazolinone Derivatives /
المؤلف
El-Hity, Gamal Abd El-Rahman.
هيئة الاعداد
باحث / جمال عبد الرحمن الهيتى
مشرف / محمد أنور عبده
مناقش / عبد الماجد امين سمور
مناقش / ابراهيم فتحى زايد
الموضوع
Chemistry.
تاريخ النشر
1990.
عدد الصفحات
137 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
تاريخ الإجازة
1/1/1990
مكان الإجازة
جامعة طنطا - كلية العلوم * - Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present work is a part of a program deals with the design and synthesis of some nitrogen bridge heterocyclic ring systems and their reactivity towards different monosugar moieties. The study on different selected substitution in correlation with their spectral and biological activity was also considered. To fulfill this 6-substituted 2-aryl-3,1-benzoxazin-4-ones were prepared by the action of 5-substituted anthranilic acid with the corresponding aroyl chloride in the presence of pyridine as a solvent. The 6-substituted 2-aryl-3-amino- 4(3H>-quinazolinones (LXIII > were also prepared by the a-g action of hydrazine hydrate with the corresponding benzoxazinone. C 13 N-Gl ycosides of 6-substituted 2-aryl-3-amino-4C 3H3 -quinazoP i ones:- The reactivity of 6-substituted 2-aryl-3-amino-4(3H)- quinazolinones (LXIlI ) towards D-monosugars e.g. D-glucose, a-e D-galactose thexoses) and D-ribose (pentose), and L-sugars e.g. L-arabinose was explored. 6-Substituted 2-aryl-3-CN-(Dglucopyranosyl) lamino-4(3H)-quinazolinones (LXIV )