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Abstract The present work is a part of a program deals with the design and synthesis of some nitrogen bridge heterocyclic ring systems and their reactivity towards different monosugar moieties. The study on different selected substitution in correlation with their spectral and biological activity was also considered. To fulfill this 6-substituted 2-aryl-3,1-benzoxazin-4-ones were prepared by the action of 5-substituted anthranilic acid with the corresponding aroyl chloride in the presence of pyridine as a solvent. The 6-substituted 2-aryl-3-amino- 4(3H>-quinazolinones (LXIII > were also prepared by the a-g action of hydrazine hydrate with the corresponding benzoxazinone. C 13 N-Gl ycosides of 6-substituted 2-aryl-3-amino-4C 3H3 -quinazoP i ones:- The reactivity of 6-substituted 2-aryl-3-amino-4(3H)- quinazolinones (LXIlI ) towards D-monosugars e.g. D-glucose, a-e D-galactose thexoses) and D-ribose (pentose), and L-sugars e.g. L-arabinose was explored. 6-Substituted 2-aryl-3-CN-(Dglucopyranosyl) lamino-4(3H)-quinazolinones (LXIV ) |