الفهرس | Only 14 pages are availabe for public view |
Abstract The diagnostic value of the pattern reversal visual evoked cortical potential (PRVEP), brainstem auditory (BAEP) and the somatosensory evoked potential (SEP) has been assessed in 15 healthy subjects and 45 patients with suspected diagnosis of multiple sclerosis (MS). The patients group satisfied McAlpine criteria for definite, probable or possible diagnosis of MS. The overall incidence of abnormalities was 78% for SEP, 62% for BAEP and 56% for VEP of all patients with MS. Of 25 MS patients with delayed VEP responses, 5 (20%) patients had neither history nor signs of optic neuritis. Similarly, of 28 and 35 patients with abnormal BAEPs and SEPs respectively, 9 (32%) and 13 (34%) had no clinical signs of dysfunction. These finding indicate that subclinical lesions of the visual, auditory and sensory pathways can be readily detected with EP studies, which helps to define a multifocal disease process and useful value in establishing the diagnosis of the disease particularly in those who do not have clinical evidence of CNS involvement. |