الفهرس | Only 14 pages are availabe for public view |
Abstract Rheumatic heart is generally considered to be a contraindication to the use of hormonal contraceptives. thise clinical impression is based on some theoritical considerations and not based on clinical trials. The reduced estrogen dosage in recently available contraceptive pills (Trivolar) and the introduction of injectable progestin ( Noristerat) suggest that a clnical trial of these contraceptives in women with rheumatic heart disease is warrented. Despite the widespread attention to the cardiovascular effects of hormonal contraceptives little is known of their influence on left ventricular size and function Also it is not known perfectly if there is increased risk of thromboembolic disease associated with the triphasic pills ( Trivolar) or with the progestin - only contraceptive ( Noristerat ). The aim of this work was to assess the effects of Trivolar and Noristerat on the left ventricular size and function of both normal and rheumatic females by the use of Echocardiography and systolic time intervals and to evaluate the effects of these contraceptives on the coagulation system through measurements of the plasma clotting factors. |