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Abstract The discovery of Helicobacter pylori ”H. pylori” is the most significant advance made in gastroduodenal pathology this century. It is the most important cause of chronic gastritis and the major etlological factor responsible for duodenal ulcer and probably for gastric ulcer as well. It may play an important role in the pathogenesis of gastric cancer1’2’* 5V The organism posseses a powerful urease activity that enables it to survive in the acidic enviroment- of the gastric lumen* \ .Helicobacter pylori has been identified in a large proportion of gastric biopsies of patients with various gastroduodenal diseases^ and in asymptomatic individuals^. |