الفهرس 
Historical ReviewOnly 14 pages are availabe for public view
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Abstract
Helicobacter pylori (H pylori) infection of the gastric antral mucosa is probably the most common chronic bacterial infection In man, being present tn approximately half of the adult population of the world. Its prevalence increases with age, from approximately 10% in those under 10 years to 70% in those more than 65 years of age. The rising prevalence with age can be explained by the fact that once contracted, the infection tends to become chronic and usually persists Indeflnltly.Since the first isolation of H pylori from antral biopsy specimens by Warren and Marshall ’ from Australia, the association of this organism with various gas trod uodenaJ disorders (GDDs) generated much interest. The reason for this upsurge in interest In this infection is the strong evidence that it plays an important role in the pathogenesis of duodenal ulcer (DU) disease. Almost all patients with DUs have the Infection and eradicating it with antibiotics and bismuth salts significantly reduces the ulcer relapse rate. The correlation between eradication and ulcer healing , and between non-eradication and ulcer persistence, suggests an aetlological role for H pylori.